CCL2 Protein
(2 references)Quick Overview for CCL2 Protein (ABIN935595)
Target
See all CCL2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
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Characteristics
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Purified recombinant Mouse MCP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag,Biotin)
CCL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag)CCL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His tag)CCL2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) protein (Biotin)CCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA, FACS Active
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-148) protein (His-IF2DI Tag)CCL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) protein (His tag)CCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96) (Active) protein (His tag)CCL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-148) protein (His-IF2DI Tag)CCL2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 2 (CCL2) protein (His tag)CCL2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) proteinCCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in sterile water to 0.1-1.0 mg/mL. Allow to set for at least 30 minutes.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
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: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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Alternative Name
- MCP1
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Background
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The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species.
Alternative Names: MCP-1 protein, MCP 1, MCP1, MCP-1 protein, MCP-1 protein, MCP 1 protein, Monocyte Chemotactic Protein-1 protein, MCP-1, CCL2 protein -
Molecular Weight
- 13.8 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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